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ARTICLE
July 2004
Emergency Rooms Unprepared for Bio-Attacks
by Joe Pappalardo
Of all the safety nets designed to cope with a biological attack in U.S. cities,
emergency rooms are among the least prepared, lacking diagnostic tools and trained
personnel, experts told a Senate panel.
“Emergency rooms are overcrowded, understaffed and have almost no surge
capacity to handle a mass casualties,” Harvey Meislin, head of the University
of Arizona’s Department of Medicine, told the Senate’s subcommittee
on terrorism, technology and homeland security.
Among the technologies that would help fill the gaps is a diagnostic tool that
would identify exposure to a biological agent definitively, with a simple blood
test, researchers and proponents said. Armed with such a device, emergency room
personnel could identify those infected from the “walking worried”
and alert higher authorities to the presence of a natural or manmade outbreak.
Current pathogen identification tests require growing cultures or testing against
antibodies, which take 24 to 48 hours.
The equipment proposed by the Arizona researchers would use the reactions of
individual genes to biological agents to identify them, giving an ER doctor
or nurse the power to make conclusive diagnoses in five minutes. The technology,
however, still remains several years away.
“The problem is getting the device to a level of sensitivity and specificity,”
Meislin said.
Sen. Jon Kyl and Rep. J.D. Hayworth, both Arizona Republicans, requested $25
million for medical research for biological preparedness as part of the Department
of Defense appropriations. “Rather than attempting, at great cost, to
set up sensors across the nation,” said Kyl, who chairs the subcommittee,
this project “would quickly determine whether symptoms of patients presenting
themselves to emergency rooms were the result of normal diseases or biological
agents.”
However, other politicians expressed skepticism about the technology. “I
don’t understand how a clinical response is very helpful. By then, it’s
too late,” said Sen. Diane Feinstein, D-Calif.
The experts were quick to say the hypothetical diagnostic tool would be best
used in conjunction with point detectors.
“These are not mutually exclusive,” said Paul Keim, director of
pathogen genomics at TGen Inc. and forensics expert who analyzed DNA evidence
from the 2001 anthrax attack on the Senate. “How much coverage do you
want, and how much do you want to pay for it?”
Keim pointed out that emergency rooms are the catch-all for the sick, making
them a logical place to screen for agents. Furthermore, diagnostic tools would
be used daily to treat patients, reducing strains on limited emergency care
resources.
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